A molecule with revolutionary properties

Preventive action

Pharm’Aging does not pretend to promise you utopian rejuvenation. However, its anti-aging active ingredient will be your major asset in “well aging”. Its effect is scientifically proven and has an action whatever your age.


15 years of research


In 2002, Dr SASAKI undertook research to develop new molecules capable of treating complications linked to diabetes and certain neurodegenerative diseases such as Parkinson’s and Alzheimer’s.

These 15 years of research have enabled Doctor SASAKI to perfect these molecules, leading to several publications and the filing of 3 successive patents.



With the help of other researchers, namely Dr LOHOU, Dr SONNET and Dr BOULLIER, they have developed two new families of molecules having an anti-AGE and anti-ALE-effect with potential applications in cosmetics, treatment of the side effects of diabetes and neurodegenerative diseases.


Patented active ingredient


This project initiated by Doctor SASAKI for over 15 years has enabled the filing of 3 patents, the last filing of which is protected internationally at the names of the National Center for Scientific Research (CNRS), the National Institute of Health and Medical Research (INSERM), the Picardie Jules Verne University (UPJV) and the Amiens Picardie University Hospital Center (CHU d’Amiens).


So this is the 3rd generation of molecules which is patented internationally.


These results have been published in a prestigious scientific journal: : Lohou et al, European Journal of Medicinal Chemistry, 2016 .


This patent is held exclusively by the company Pharm’Aging.


Triple action


These families of molecules protected by this patent have several competitive advantages for the development of a cosmetic ingredient:

  • une activité anti-oxydant et anti-peroxydation lipidique à très faible concentration avec une efficacité supérieure à la molécule référente du marché (la vitamine E),
  • une activité anti-glycation à très faible concentration avec une efficacité supérieure à la molécule référente du marché (la carnosine),
  • une absence de toxicité.


The LygalamineTM molecule was born from these conclusions.


From this innovation stemming from biomedical research, Pharm’Aging has made it a revolutionary anti-aging cosmetic active ingredient.


LygalamineTM is the only active ingredient that effectively combats the effects of lipid peroxidation and glycation, in addition to an antioxidant action.

The efficacy of this active ingredient has been scientifically confirmed during extensive skin testing. The elastic fibers present in the dermis and responsible for skin elasticity have been quantified. The degradation of these fibers leads to a loss of skin elasticity and the appearance of wrinkles.

We have shown that LygalamineTM makes it possible to obtain 50% more elastic fibers from the 9th day of use, i.e. 22% more efficiency compared to certain reference molecules on the market.

This active has been developed specifically to help women and men prevent skin aging.


You can exclusively find this revolutionary anti-aging active ingredient in our Artejia face care range, the perfect beauty equation for your skin.

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